Pharmacokinetic
Pharmacokinetic (PK) data is a key requirement in the evaluation of new drugs and formulations. A quantitative measure of drug exposure is essential for the sound interpretation of pre-clinical efficacy studies. PK data is also requisite before toxicology studies can be performed.
PK samples are collected at various time points as per protocol and analyzed for drug concentrations. The time points depending on the nature of compound and route of administration.
Species offered:
- Mouse
- Rat
Delivery method:
- Single dose
- Multiple dose
- Infusion
- Cassette dosing
Route of administration
- Oral (PO)
- Intraperitoneal (IP)
- Subcutaneous (SC)
- Intramuscular (IM)
- Intravenous (IV)
- Topical
- Intranasal
- Subcutaneous (SC)
- Intraocular
- Intra-rectal
Sampling:
- Blood-Plasma or Serum
- Urine
- Feces
- Tissue or organ
Pharmacokinetic study in disease model
Invitek offers Pharmacokinetics in disease models for better understanding of absorption and bioavailability.
Toxicokinetics
Toxicokinetics used primarily for establishing relationships between exposures in toxicology experiments in animals and corresponding exposures in humans.
Plasma samples generated in toxicology studies and the resultant concentration data used for interpreting the result using the industry-standard software.